Are Hangovers Caused by a Glutamine Rebound?
Glutamine is an important amino acid that contributes to many functions within the body, and is essentially a building block of proteins in the body, and is an important part of the immune system. After a solid day or night of drinking, a person will not necessarily sleep soundly, which is why they feel so tired when they wake up. The body is on the rebound from the alcohol, that causes the depressive effects on the central nervous system. The consumption of alcohol inhibits the production of glutamine, which is a natural stimulant in the body. When the drinking stops, the body realizes it has to make up for lost time, and produce more glutamine.
When someone who drinks beer, wine, or spirits is trying to sleep, their brain is being stimulated by an increased amount of glutamine preventing deep sleep. This glutamine rebound can also contribute to the tremors, anxiety, increased blood pressure, and restlessness. Alcohol is also absorbed directly through the stomach, and the cells that line the stomach become irritated and produce the secretion of hydrochloric acid in the stomach. The nerves send the message to the brain that the stomach is in trouble, and vomiting will ensue. Vomiting can lessen the symptoms of a hangover because it does evacuate some of the toxins. The irritation in the stomach causes the symptoms of diarrhea and lack of appetite, which contributes to all the other symptoms of a hangover.